HomeProducts Medical And Food Grade Medical Grade DuPont Liveo 366 - 35% Dimethicone NF Emulsion
DuPont Liveo 366 - 35% Dimethicone NF Emulsion

DuPont Liveo 366 - 35% Dimethicone NF Emulsion

Liveo 366 35% Dimethicone NF Emulsion is a high-purity, water-dilutable silicone lubricant designed for medical and pharmaceutical applications. It serves as a modern, REACh-compliant alternative for the siliconization of healthcare components like glass syringes and rubber stoppers.
PRODUCTS DESCRIPTION

The DuPont Liveo 366 is an aqueous emulsion containing 35% Dimethicone NF (Polydimethylsiloxane) with a viscosity of 350 cSt. Formulated specifically for medical device manufacturers, this white, liquid emulsion is free from parabens and OPE surfactants, ensuring it meets strict global regulatory standards while providing a stable, hydrophobic lubricating film after application.

Medical Grade Protective 35% Dimethicone NF Emulsion is a silicone-based medical ingredient designed for pharmaceutical, healthcare and personal care formulation applications. With 35% dimethicone content, excellent emulsion stability and reliable skin protection performance, it provides manufacturers with a consistent raw material solution for developing protective creams, barrier products and silicone-based healthcare formulations.

Products parameters

Active Ingredient: 35% Dimethicone (Polydimethylsiloxane)

Base Fluid Viscosity: 350 cSt

pH Level: Approximately 5.0

Appearance: White, liquid emulsion

Packaging: 454g, 16kg


Key features

  • Water-Dilutable System: Designed for easy dispersion in water to allow controlled application of silicone fluid without the need for organic solvents.

  • REACh & Regulatory Compliance: Formulated without octylphenyl ethoxylates (OPE) or parabens to meet the latest European EChA requirements.

  • High-Stability Lubrication: Forms a durable, hydrophobic film that remains stable after "bake-on" siliconization processes.

  • National Formulary (NF) Standard: Contains dimethicone qualified to meet both Dimethicone NF and Ph. Eur. monograph requirements for pharmaceutical purity.

  • Excellent Wetting Properties: Features superior surface coverage on various substrates, ensuring uniform lubrication even at low concentrations.


1. Medical Grade Dimethicone NF Formulation

This 35% Dimethicone NF Emulsion is developed with a controlled dimethicone formulation suitable for medical and healthcare-related applications. The NF-grade ingredient characteristics provide consistent quality and reliable performance for manufacturers requiring stable silicone materials in professional formulations.

Its controlled composition helps support product consistency during large-scale manufacturing and reduces variations caused by unstable raw materials.


2. Stable 35% Active Silicone Content

The product contains 35% dimethicone, providing a balanced silicone concentration for different formulation requirements. The stable active content helps manufacturers achieve predictable product performance while maintaining good processing flexibility.

This characteristic makes it suitable for creams, lotions, protective formulations and other products where controlled silicone performance is required.


3. Excellent Barrier Protection Performance

Dimethicone is widely used in protective formulations due to its ability to form a smooth and breathable layer on the skin surface. This emulsion helps improve skin feel while supporting moisture retention and surface protection.

For healthcare product manufacturers, it provides a functional silicone ingredient that enhances the protective performance of finished products.


4. Reliable Emulsion Stability

The silicone emulsion system is designed to maintain uniform dispersion of dimethicone within formulations. Stable dispersion helps improve production consistency and reduces formulation problems caused by uneven ingredient distribution.

This allows manufacturers to achieve more reliable batch quality during repeated production cycles.


5. Smooth Processing and Formulation Compatibility

The emulsion provides good spreadability and compatibility with different formulation systems. It can help improve the texture, application experience and overall performance of finished healthcare and personal care products.

Its processing advantages make it suitable for OEM manufacturers developing customized silicone-based formulations.


Application
  • Glass Syringe Siliconization: Applied to the internal barrels of glass syringes to ensure smooth plunger movement and reduced injection force.

  • Medical Device Lubrication: Used on plastics, metals, and rubber components to reduce friction and improve functional performance.

  • Parenteral Container Treatment: Ideal for coating the interior of vials and glass containers to prevent drug adsorption and ensure total fluid recovery.

  • Rubber Stopper Coating: Acts as a release agent and lubricant for rubber closures to facilitate high-speed processing and assembly.

  • General Medical Fabrication: Serves as a versatile demolding agent in the manufacturing of specialty medical devices.


1. Medical Barrier Cream Manufacturing

This dimethicone emulsion is suitable for manufacturers producing medical barrier creams designed to protect skin surfaces and improve comfort during daily use.

Its silicone protection properties help create formulations requiring smooth application, moisture control and stable performance.


2. Pharmaceutical Topical Formulations

Pharmaceutical manufacturers use silicone-based ingredients in topical products where consistent texture, skin conditioning and protective properties are required.

The 35% Dimethicone NF Emulsion provides a reliable ingredient option for creams, ointments and other external-use formulations.


3. Healthcare Skin Protection Products

Healthcare products often require ingredients that support skin protection and improve application performance.

This silicone emulsion helps manufacturers develop protective skincare products with stable formulation characteristics and comfortable skin feel.


4. Personal Care Product Development

The product can be applied in personal care formulations requiring silicone-based conditioning, smooth texture and improved sensory performance.

It supports manufacturers producing lotions, creams and skincare products with consistent quality requirements.


5. OEM Silicone-Based Formulation Projects

For OEM and private-label manufacturers, raw material consistency directly affects finished product quality.

This dimethicone emulsion provides a stable silicone ingredient solution for customized healthcare, pharmaceutical and personal care product development.


DuPont Liveo 366 - 35% Dimethicone NF Emulsion Storage and Handling

To maintain product stability, dimethicone emulsion should be stored in a controlled environment away from extreme temperatures and direct sunlight. Proper storage conditions help preserve emulsion structure and maintain consistent performance during the product shelf life.

During transportation and production handling, manufacturers should follow recommended storage guidelines to avoid unnecessary changes in material performance.


Get Your Dimethicone NF Emulsion Solution

Developing a medical or personal care formulation that requires stable silicone emulsion performance?

Share your formulation requirements, application goals and production plans with our team to receive a suitable 35% Dimethicone NF Emulsion recommendation tailored to your product development needs.


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